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1.
Safety and Health at Work ; 13:S182, 2022.
Article in English | EMBASE | ID: covidwho-1677080

ABSTRACT

Introduction: Infection by the SARS-CoV-2 virus that causes COVID-19 may lead to symptoms that persist after the disease is cured. Objective: to assess the epidemiological profile of the workers and their work capacity after convalescence from the symptomatic disease. Methods: Descriptive, cross-sectional study of 28 workers who had COVID-19 and were treated at the ADT (Outpatient Clinic for Occupational Diseases) of HCPA between April and June 2021. A clinical evaluation was performed and a questionnaire was applied about factors associated with infection by SARS-CoV-2 and the sequelae of the disease. Results: 63% of the workers were female and 81.5% were self-declared white. 61.5% of the cases had a formal job and 83.3% were away from work for more than 15 days. As to hospitalizations, 44% were in beds of the intensive care unit and 32% on the medical ward. The source of contagion was associated with the work environment in 20% of the cases and 73.9% of the patients had at least one chronic disease. At the time of diagnosis, the most prevalent symptoms were fever (54.2%), coughing (45.3%), dyspnea (45.8%), myalgia (33.3%) and headache (25%). At the first outpatient visit the most common persisting symptoms were: fatigue/tiredness (54.2%), myalgia (33%), anxiety (16.7%) and hair loss (20.8%). Conclusion: Incapacity for work was present in all cases studied. The complexity of care of patients who continue to have symptoms after convalescing from COVID-19 requires an interdisciplinary evaluation, which was achieved by creating an outpatient clinic involving more than 10 medical specialties to evaluate these cases.

2.
European Review for Medical & Pharmacological Sciences ; 25(8):3365-3374, 2021.
Article in English | MEDLINE | ID: covidwho-1208720

ABSTRACT

OBJECTIVE: Healthcare workers are at risk for COVID-19 contamination. It is important to protect them in order to reduce nosocomial transmission and maintain the assistance capacity of health systems. To evaluate the diagnostic test and retest strategy with RT-PCR for SARS-CoV-2 and factors associated with the diagnosis of COVID-19 among healthcare workers. PATIENTS AND METHODS: Cross-sectional study carried out in a Brazilian hospital. From April 27 to June 16, 2020, symptomatic healthcare workers underwent an RT-PCR test on upper respiratory tract specimens as soon as possible and, if negative, it was repeated close to the 5th day of symptom evolution. Working areas were divided into assistance areas dedicated or not dedicated to COVID-19 and non-assistance areas. The type of activity was divided into assistance or non-assistance activity. RESULTS: 775 individuals were evaluated. 114 were diagnosed with COVID-19, of whom 101 followed the testing protocol. A second RT-PCR identified five (4.9%) of the positive cases. Working in an area dedicated to patients with COVID-19 was more prevalent among positive cases (35.1% x 19.8%, p=0.001) as well as working in an assistance activity (80.7% x 70.8%, p=0.031). CONCLUSIONS: A second RT-PCR test after the 5th day of symptom evolution showed limited diagnostic improvement. The adoption of a single test-based strategy, carried out at the right time after the onset of symptoms, allows the optimal use of resources. Working in a COVID-19 dedicated area and in direct contact with patients is related to a higher prevalence of COVID-19 among symptomatic healthcare workers.

3.
Eur Rev Med Pharmacol Sci ; 24(23): 12579-12588, 2020 12.
Article in English | MEDLINE | ID: covidwho-995018

ABSTRACT

Management of SARS-CoV-2 requires safe decision-making to minimize contamination. Healthcare workers and professionals in confined areas are affected by the risk of the activity and the environment. Isolation of contaminated workers and healthcare professionals requires clinical and diagnostic criteria. On the other hand, interrupting the isolation of healthcare employees and professionals is critical because diagnostic tests do not support clinical decisions. In addition to defining the best test in view of its accuracy, it is necessary to consider aspects such as the stage of the disease or cure, the viral load and the individual's own immunity. Uncertainty about natural and herd immunity to the disease leads to the development of appropriate antivirals, diagnostic tests and vaccines.


Subject(s)
COVID-19 Nucleic Acid Testing , COVID-19 Serological Testing , COVID-19/transmission , Patient Isolation/standards , Adaptive Immunity/immunology , Antibodies, Viral/immunology , Antigens, Viral/immunology , Bronchoalveolar Lavage Fluid/chemistry , Bronchoalveolar Lavage Fluid/virology , COVID-19/diagnosis , COVID-19/immunology , COVID-19/prevention & control , COVID-19 Testing , Clinical Decision-Making , Feces/chemistry , Feces/virology , Health Personnel , Humans , Immunoglobulin G/immunology , Immunoglobulin M/immunology , Nasopharynx/chemistry , Nasopharynx/virology , Patient Isolation/methods , RNA, Viral/analysis , SARS-CoV-2 , Sputum/chemistry , Sputum/virology , Viral Load
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